Levent M Akyürek Selected Research

Microfilament Proteins (Actin Binding Proteins)

1/2022	Filamin A increases aggressiveness of human neuroblastoma.
1/2019	Targeting Filamin A Reduces Macrophage Activity and Atherosclerosis.
2/2015	Deficiency of filamin A in endothelial cells impairs left ventricular remodelling after myocardial infarction.
2/2014	Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response.
2/2011	Filamin a mediates HGF/c-MET signaling in tumor cell migration.
10/2010	A positive relationship between filamin and VEGF in patients with lung cancer.
3/2007	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.

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Levent M Akyürek Research Topics

Disease

11	Neoplasms (Cancer) 01/2022 - 10/2010
5	Hypoxia (Hypoxemia) 01/2017 - 07/2008
4	Atherosclerosis 01/2020 - 05/2010
3	Neuroblastoma 01/2022 - 11/2014
3	Melanoma (Melanoma, Malignant) 11/2021 - 10/2015
3	Atherosclerotic Plaque (Atheroma) 01/2019 - 05/2010
3	Myocardial Infarction 02/2015 - 09/2009
2	Neoplasm Metastasis (Metastasis) 11/2021 - 10/2015
2	Disease Progression 01/2017 - 02/2010
2	Inborn Genetic Diseases (Disease, Hereditary) 02/2010 - 10/2007
1	Sarcoma (Soft Tissue Sarcoma) 11/2021
1	Respiratory Tract Diseases (Respiratory Tract Disease) 06/2021
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 02/2021
1	Colorectal Neoplasms (Colorectal Cancer) 02/2021
1	Fibrosarcoma 01/2018
1	Prostatic Neoplasms (Prostate Cancer) 01/2018
1	Lymphatic Metastasis 10/2015
1	Adenocarcinoma of Lung 08/2012
1	Lung Neoplasms (Lung Cancer) 10/2010
1	Myocardial Ischemia (Ischemic Heart Diseases) 06/2010
1	Ischemia 06/2010
1	Rupture 01/2010
1	Carotid Stenosis (Carotid Artery Stenosis) 01/2010
1	Pathologic Constriction (Stenosis) 01/2010
1	Hemorrhage 01/2010
1	Hyperemia 09/2009
1	Infarction (Infarctions) 09/2009
1	Larsen Syndrome 03/2007
1	Boomerang dysplasia 03/2007
1	Spondylocarpotarsal synostosis 03/2007
1	Infections 09/2003
1	Acquired Immunodeficiency Syndrome (AIDS) 09/2003
1	Neointima 04/2003

Drug/Important Bio-Agent (IBA)

12	FilaminsIBA 01/2022 - 03/2007
7	Microfilament Proteins (Actin Binding Proteins)IBA 01/2022 - 03/2007
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2010
3	CalpainIBA 01/2019 - 02/2014
2	Messenger RNA (mRNA)IBA 01/2022 - 11/2021
2	Small Interfering RNA (siRNA)IBA 01/2022 - 09/2009
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2021 - 10/2010
2	AntioxidantsIBA 02/2021 - 10/2015
2	Acetylcysteine (Siran)FDA LinkGeneric 02/2021 - 10/2015
2	Vitamin E FDA LinkGeneric 02/2021 - 10/2015
2	Proprotein Convertase 9IBA 01/2020 - 01/2019
2	calpeptinIBA 01/2019 - 01/2018
2	Long Noncoding RNAIBA 12/2018 - 11/2014
2	Biological ProductsIBA 08/2012 - 04/2003
2	CollagenIBA 01/2010 - 09/2009
1	TensinsIBA 11/2021
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/2021
1	Oxygen (Dioxygen)IBA 11/2021
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 11/2021
1	Matrix Metalloproteinases (MMPs)IBA 11/2021
1	Angiogenesis InhibitorsIBA 11/2021
1	RNA (Ribonucleic Acid)IBA 11/2021
1	Transcription Factors (Transcription Factor)IBA 06/2021
1	Pharmaceutical PreparationsIBA 02/2021
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 01/2020
1	LDL Receptors (LDL Receptor)IBA 01/2019
1	calpain inhibitorsIBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 01/2017
1	Adenosine Triphosphate (ATP)IBA 01/2017
1	Glutathione (Reduced Glutathione)IBA 10/2015
1	Glutathione Disulfide (GSSG)FDA LinkGeneric 10/2015
1	6- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA 10/2015
1	Phosphotransferases (Kinase)IBA 10/2015
1	Biomarkers (Surrogate Marker)IBA 11/2014
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 02/2011
1	ParaffinIBA 10/2010
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 06/2010
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 05/2010
1	Apolipoproteins E (ApoE)IBA 05/2010
1	CholesterolIBA 05/2010
1	ApolipoproteinsIBA 05/2010
1	EndoglinIBA 02/2010
1	Adenosine (Adenocard)FDA LinkGeneric 09/2009
1	Protein Disulfide-IsomerasesIBA 09/2009
1	Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA 07/2008
1	VaccinesIBA 09/2003

Therapy/Procedure

3	Therapeutics 08/2012 - 10/2010
1	Aftercare (After-Treatment) 01/2018
1	Endarterectomy (Thromboendarterectomy) 01/2010
1	Stents 04/2003